The proper clinical biological preservation of the hair follicle tissue is a crucial factor in successful hair transplantation. In modern hair transplantation, it is often necessary for an average of 6 to 8 hours to remove and transfer thousands of hair follicles. Body and without proper blood supply, is very sensitive and important, because of its impact on the success of the process of agriculture later. Since 2013, Clin Medica has been using Hypothermosol FRS as a storage solution, instead of the normal saline solution used to maintain hair stings during the hair transplant process, to keep the follicles extracted from the donor area, in the best possible way.
What is Hypothermosol?
Is a new refrigerant storage medium designed to maintain the vitality of the extracted bulbs by providing maximum biological storage stability at 2-8 ° C. This method is the ideal method for reducing the sensitivity of the molecular cell resulting from low temperature exposure and re-warming Cells and tissues during transplantation.
This is done by providing appropriate pH, supporting osmosis, energy substrates, and ionic concentrations to balance cells at low temperatures, and has been shown to be more effective in promoting cell survival after transplantation compared to other methods used in hair transplantation.
Cell damage During hair transplantation, hair follicles extracted from the donor area undergo a number of stress factors during the hair transplant process:
Stress before and during the extraction of the follicular units from the donor area.
During the eradication of grafts.
During the bait retention phase.
Under normal conditions, human cells and tissues are made up of the isotonic equilibrium (OCD) and are carried out by the cell membrane pumps driven by ATP. The main ionic components include sodium, potassium, calcium, magnesium, and chloride.
The environment inside and outside the cell is completely different from each other, which subsequently regulates the negative flow of water inside and outside the cells.
At 37 ° C, there is a fluid balance at the ends of the cell. The nutrients of the cell flow through the cell membrane into it while the harmful substances and waste are expelled, and the process continues for the cells to control their life.
But when hair follicles are removed from the body even for a short period, there are many potentially harmful consequences due to the absence of nutrients such as glucose and oxygen which makes cells unable to generate energy to maintain normal vitality.
Save cells with refrigeration:
The cooling was up to 2-8 ° C, the preferred process mechanism for storing tissue cells and organs for short periods of time and as a result the metabolism slows down approximately 50% per 10 ° C when temperatures drop below normal human body temperature.
This method has been used to preserve cells, tissues and organs (such as the heart and kidney) in abnormal conditions (transferred from one body to another) and have been widely used in maintaining hair follicles in hair transplantation. Damage to grafts leads to cell death, especially when saline solutions are used as a storage solution, so hypothermosol has been used as a more effective solution to keep baits as long as possible.
Comparison of Hypothermosol and Saline Solution:
When comparing the methods adopted to maintain the outside grafts, it is estimated that the grafts stored in saltwater for five days did not remain alive, while the baits stored in the HypoThermosol FRS showed forty-four percent of the remaining 44% Five days, which means that in less than a day of planting, all the follicles remain mostly alive and re-implantable with the use of HypoThermosol FRS solutions. Since the conservation of grafts for hair transplantation is the most important to successful hair transplantation, This comparison and testing highlights the importance of using HypoTherm Osol to improve the survival of grafts in a suitable position for implantation, and maximize results for those interested in hair transplantation.
Storing hair transplantation outside the body greatly affects the quality of hair transplants.
There are many studies and views on the mechanism of maintaining grafts extracted from the donor area outside the body, experts and surgeons have adopted for many years several ways to maintain grafts, until things reached the stage of chaos sometimes. But Clin Medica seeks to achieve the best results for hair transplantation, the art of Clin Medica experts put the following questions before them and worked to get the best results:
Question 1: How well do storage media affect the final quality of the transplant?
Question 2: Which of the storage media provides the greatest protection for baits during hair transplantation?
For years, Veclin Medica experts have carried out important studies in this field, followed up on what experts around the world have done, and have also found the final conclusion that the best methods to keep grafts in a healthy and appropriate position for transplantation are by using HypoThermosol, after comparing results with other methods .
Maximize the usefulness of hair transplantation after storage outside the vivo
To achieve complete success in hair transplantation, the cell must be supported under low temperature conditions, to achieve maximum benefit from the blood stasis caused by low temperature, we need a solution that keeps the environment inside the cells balanced.
Studies have given that the optimal solution would be depending on the understanding of what happens inside the cells specifically to support tissue samples during cryogenic storage, and treatment